Simulation of survival studies based on simulated gene expression level and patient data. Includes functions to generate such data. Resulting error and power rate can be visualized. Can be used for sample size or power estimation when planning a study.
This package provides methods described in:
Andreas Leha, Tim Beißbarth, and Klaus Jung
Sequential Interim Analyses of Survival Data in DNA
Microarray Experiments,
BMC Bioinformatics, 2011
www.biomedcentral.com/1471-2105/12/127 [ bib ]
Install with
install.packages("survGenesInterim", repos="http://R-Forge.R-project.org")
The project summary page you can find here.